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Non-canonical mTORC2 signaling regulates brown adipocyte lipid catabolism through SIRT6FoxO1

Collagenase-dispersed cells (adapted from refs 10 and 11) 1

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At week 52, 76.9%, 70.3%, and 72.6% of patients with 2-week dosing, 4-week dosing, and 4- to 2-week dosing, respectively, achieved a PSSI score of 0